TY - JOUR
T1 - Genotypic sex determination in teleosts
T2 - Insights from the testis-determining amhy gene
AU - Hattori, Ricardo Shohei
AU - Strüssmann, Carlos Augusto
AU - Fernandino, Juan Ignacio
AU - Somoza, Gustavo Manuel
PY - 2013/10/1
Y1 - 2013/10/1
N2 - The master sex-determining genes identified so far in fishes are clearly not conserved, as evidenced by several unrelated genes reported to play critical roles in sex determination. In this study, we reviewed the molecular process of sex determination in the Patagonian pejerrey Odontesthes hatcheri, an emerging model due to the recent discovery that a Y-chromosome linked, duplicated copy of the anti-Müllerian hormone gene, amhy plays a pivotal role in sex determination. A comparative analysis with other newly found sex-determining genes of teleost fish, DMY/. dmrt1bY, sdY, amhr2, and gsdfY is performed and alternative ideas are proposed to explain the mechanism involved in the rise of various types of non-homologous sex-determining genes.
AB - The master sex-determining genes identified so far in fishes are clearly not conserved, as evidenced by several unrelated genes reported to play critical roles in sex determination. In this study, we reviewed the molecular process of sex determination in the Patagonian pejerrey Odontesthes hatcheri, an emerging model due to the recent discovery that a Y-chromosome linked, duplicated copy of the anti-Müllerian hormone gene, amhy plays a pivotal role in sex determination. A comparative analysis with other newly found sex-determining genes of teleost fish, DMY/. dmrt1bY, sdY, amhr2, and gsdfY is performed and alternative ideas are proposed to explain the mechanism involved in the rise of various types of non-homologous sex-determining genes.
KW - Amhy
KW - GSD
KW - Odontesthes hatcheri
KW - Patagonian pejerrey
KW - Sex-determining genes
UR - https://www.scopus.com/pages/publications/84884416289
U2 - 10.1016/j.ygcen.2013.03.019
DO - 10.1016/j.ygcen.2013.03.019
M3 - Artículo de revisión
C2 - 23602719
AN - SCOPUS:84884416289
SN - 0016-6480
VL - 192
SP - 55
EP - 59
JO - General and Comparative Endocrinology
JF - General and Comparative Endocrinology
ER -